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Our lab studies various aspects of chromosome biology ranging from the maintenance of chromosome ends by telomerase to meiosis, hybridization and ploidy.

 

 

Lab News

 

December 2014 | "Neaves' whiptail lizard: the first known tetraploid parthenogenetic tetrapod (Reptilia: Squamata: Teiidae" was published in Breviora.

November 2014 | Peter and Aracely attended the HHMI Science Meeting in Bethesda, Maryland. Aracely presented a poster on "Oogenesis in unisexual whiptail lizards".

 

September 2014 | Congrats to the new graduate, Summer!

 

September 2014 | Peter and Allie attended the RiboClub annual meeting in Orford, Canada. Allie presented a poster on "Inhibition of splicing affects human telomerase RNA biogenesis".

 

June 2014 | Aracely Newton attended the Evolution 2014 meeting in Raleigh, North Carolina. Aracely gave an oral presentation on "Unisexual whiptail lizards find a loophole: how meiosis progresses in a species created through hybridization".

 

June 2014 | Richard, Chi-Kang, and Li all attended the 19th Annual RNA Meeting in Quebec City, Canada. Richard presented a poster on "Characterization of fission yeast tri-methyl guanosine synthase (tgs1)". Chi-Kang presented a poster on "Quality control of telomerase RNA biogenesis".

 

April 2014 | Kristi, Maggie, and Lili all attended the EMBO Conference on Telomeres, Telomerase and Disease in Brussels, Belgium. Lili gave an oral presentation on "A billion years of shelterin - conservation of interaction modules and the potential to form higher order structures." Kristi presented a poster on "Influence of environmental factors on telomerase-independent survivor formation in fission yeast" and Maggie on "In vivo selection for new telomerase RNA template regions in S. pombe."

 

Lab News Archive

 

TELOMERASE

Given the key role telomerase plays in several degenerative diseases and cancer, it is pivotal that we gain a better understanding of how the enzyme is made, recruited to chromosome ends and regulated... Read more

 

MEIOSIS AND REPRODUCTION

We are interested in the mechanisms that trigger a switch to parthenogenesis (virgin birth). In addition to providing new insights into the evolution of reproduction, we are developing a clonal vertebrate model...Read more

HYBRIDIZATION AND PLOIDY

We are using lizards of the genus Aspidoscelis to examine the immediate and long-term consequences of hybridization and ploidy changes...Read more

 

TELOMERES

We are interested in the molecular mechanism of telomere length regulation and the roles of telomeres in meiosis and regulation of gene expression...Read more