Publications • Clinical Data • Gene Expression • Proteomics Data • SNP Data
Suzanne Vernon, CDC (4 Dec 2005 e-mail):
18 Jan 2006 (efg) Background information: Q: What do the names of the tabsheets mean, i.e., COMT, CRHR1, CRHR2, MAOA, MAOB, NR3C1, POMC, SLC6A4, TH and TPH2? A: These apparently are some of the genes that are described in this paper: Also see Zurich/deCODE Linkage Mapping Set 26 Jan 2006 |
Information from "Genetic tests of biologic systems in affective disorders," Hattori, et al
about SNP Genes
(links below are to NCBI Entrez Gene information)
Neurotransmission system -- Monoaminergic neurotransmission |
||||
Symbols |
Genes |
Subcategories |
Chromosomal region |
Genomic size (bp) |
| TPH2 | Tryptophan hyroxylase 2 | 5-HT; |
12q15 |
93595 |
| SLC6A4 | Solute carrier family 6 (neurotransmitter, transporter, serotonin), member 4; (aliases HTT, SERT) |
5-HT; Transporter |
17q11.2 |
24118 |
| MAOA | Monoamine oxidase A | Multiple monoaminergic systems; Metabolic enzyme | Xp11.3 |
70206 |
| MAOB | Monoamine oxidase B | Xp11.3 |
115765 |
|
| TH | Tyrosine hydroxylase | 11p15.5 |
7887 |
|
| COMT | Catechol-O-methyltransferase | 22q11 |
27047 |
|
A Neuroendocrine system -- HPA axis |
||||
Symbols |
Genes |
Subcategories |
Chromosomal region |
Genomic size (bp) |
| POMC | Proopiomelanocortin (alias ACTH) |
Neurotransmitter; |
2q23.3 |
7665 |
| CRHR1 | Corticotropin-releasing hormone receptor 1 | Receptor | 17q21.31 |
51525 |
| CRHR2 | Corticotropin-releasing hormone receptor 2 | 7p14.3 |
29697 |
|
| NR3C1 | Nuclear receptor subfamily 3, group C, member 1; (Alias: Glucocorticoid receptor) |
5q31.3 |
123763 |
|
Updated
26 Jan 2006