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Recent Publications:

 

Parrish, M., Unruh, J., and Krumlauf, R. (2011 ePub). BAC modification through serial or simultaneous use of CRE/Lox technology. Journal of Biomedicine & Biotechnology 2011 (12 pages).

Krumlauf, R., and Levine, M. (2010). Gene expression and development. Special introduction. Developmental biology 339, 224.

Ahn, Y., Sanderson, B.W., Klein, O.D., and Krumlauf, R. (2010). Inhibition of Wnt signaling by Wise (Sostdc1) and negative feedback from Shh controls tooth number and patterning. Development 137, 3221-3231.

Wang, P., Lin, C., Smith, E.R., Guo, H., Sanderson, B.W., Wu, M., Gogol, M., Alexander, T., Seidel, C., Wiedemann, L.M., Ge, K., Krumlauf, R., and Shilatifard, A. (2009). Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II. Molecular and cellular biology 29, 6074-6085.


Tümpel, S., Wiedemann, L.M., and Krumlauf, R. (2009). Hox genes and segmentation of the vertebrate hindbrain. In HOX Genes, O. Pourquié, ed. (Burlington, Academic Press), pp. 103-137.

Parrish, M., Nolte, C., and Krumlauf, R. (2009). Hox genes expression. In Encyclopedia of Neuroscience, L.R. Squire, ed. (Oxford, Academic Press), pp. 1221-1231.

Alexander, T., Nolte, C., and Krumlauf, R. (2009). Hox genes and segmentation of the hindbrain and axial skeleton. Annual review of cell and developmental biology 25, 431-456.


Tümpel, S., Cambronero, F., Sims, C., Krumlauf, R., and Wiedemann, L.M. (2008). A regulatory module embedded in the coding region of Hoxa2 controls expression in rhombomere 2. Proc Natl Acad Sci U S A 105, 20077-20082.


Bogni, S., Trainor, P., Natarajan, D., Krumlauf, R., and Pachnis, V. (2008). Non-cell-autonomous effects of Ret deletion in early enteric neurogenesis. Development 135, 3007-3011.
 

Inoue, T., Inoue, Y.U., Asami, J., Izumi, H., Nakamura, S., and Krumlauf, R. (2008). Analysis of mouse Cdh6 gene regulation by transgenesis of modified bacterial artificial chromosomes. Dev Biol 315, 506-520.
  

Rinon, A., Lazar, S., Marshall, H., Buchmann-Moller, S., Neufeld, A., Elhanany-Tamir, H., Taketo, M.M., Sommer, L., Krumlauf, R., and Tzahor, E. (2007). Cranial neural crest cells regulate head muscle patterning and differentiation during vertebrate embryogenesis. Development 134, 3065-3075.
  

Tümpel, S., Cambronero, F., Ferretti, E., Blasi, F., Wiedemann, L.M., Krumlauf, R. Expression of Hoxa2 in rhombomere 4 is regulated by a conserved cross-regulatory mechanism dependent upon Hoxb1. (2007) Dev Biol 302: 646-660.

Nolte, C., and Krumlauf, R. (2006). Expression of Hox genes in the nervous system of vertebrates. In HOX Gene Expression, S. Papageorgiou, ed. (Austin, TX, Landes Bioscience and Springer), pp. 14-41.
  

Ellies, D.L., Viviano, B., McCarthy, J., Rey, J.P., Itasak,i N., Saunders, S., Krumlauf, R. Bone density ligand, Sclerostin, directly interacts with LRP5 but not LRP5(G171V) to modulate Wnt activity. (2006) J Bone Miner Res 21: 1738-1749.

Ellies, D.L., Krumlauf, R. Bone formation: The nuclear matrix reloaded. Cell (2006) 125: 840-2.

Tümpel, S., Cambronero, F., Wiedemann, L. and Krumlauf, R., (2006) Evolution of cis-elements in the differential expression of two Hoxa2 co-paralogous genes in pufferfish. PNAS 103: 5419-5424.

Inoue, T., Correia, K. and Krumlauf, R. (2006) Electroporation of living embryos. In Cell Biology: A laboratory handbook, 3rd Ed., J. E.Celis (ed), Elsevier Science (USA) 35-42.

Serpente, P., Tümpel, S., Ghyselinck, N. B., Niederreither, K., Wiedemann, L. M., Dollé, P., Chambon, P., Krumlauf, R., and Gould, A. P. (2005). Direct crossregulation between retinoic acid receptor b and hox genes during hindbrain segmentation. Development 132, 503-513.

Ferretti, E., Cambronero, F., Tümpel, S., Longobardi, E., Wiedemann, L. M., Blasi, F., and Krumlauf, R. (2005). The hoxb1 enhancer and control of rhombomere 4 expression: Complex interplay between prep1-pbx1-hoxb1 binding sites. Mol Cell Biol 25, 8541-8552.

Kusumi, K., Mimoto, M., Covello, K.l, Beddington, R., Krumlauf, R. and Dunwoodie, S. (2004) Dll3  pudgy  mutation differentially disrupts dynamic expression of somite genes.  Genesis 39, 115-121.           

Trainor, P., Bronner-Fraser, M., and Krumlauf, R. (2004). Neural crest cells: Development and patterning of an embryonic stem cell population. In Handbook of embryonic stem cells, L. e. al, ed. (San Diego, Elsevier), pp. 219-232.

Powles, N., Marshall, H., Economou, A., Chiang, C., Murakami, A., Dickson, C., Krumlauf, R., and Maconochie, M. (2004). Regulatory analysis of the mouse fgf3 gene: Control of embryonic expression patterns and dependence upon sonic hedgehog (shh) signalling. Dev Dyn 230, 44-56.

Mercurio, S., Latinkic, B., Itasaki, N., Krumlauf, R., and Smith, J. C. (2004). Connective-tissue growth factor modulates wnt signalling and interacts with the wnt receptor complex. Development 131, 2137-2147.

Gavalas, A., Ruhrberg, C., Livet, J., Henderson, C. E., and Krumlauf, R. (2003). Neuronal defects in the hindbrain of hoxa1, hoxb1 and hoxb2 mutants reflect regulatory interactions among these hox genes. Development 130: 5663-5679. .

Pattyn, A., Vallstedt, A., Dias, J. M., Samad, O. A., Krumlauf, R., Rijli, F. M., Brunet, J. F., and Ericson, J. (2003). Coordinated temporal and spatial control of motor neuron and serotonergic neuron generation from a common pool of cns progenitors. Genes Dev 17, 729-737.

Ivins, S., Pemberton, K., Guidez, F., Howell, L., Krumlauf, R., and Zelent, A. (2003). Regulation of hoxb2 by apl-associated plzf protein. Oncogene 22, 3685-3697.

Itasaki, N., Jones, C. M., Mercurio, S., Rowe, A., Domingos, P. M., Smith, J. C., and Krumlauf, R. (2003). Wise, a context-dependent activator and inhibitor of wnt signalling. Development 130, 4295-4305.