EDUCATION
Doctor of Philosophy,
Biochemistry-February, 2004
Master of Science, Cell
Biology-February, 2000
Bachelor of
Science-February, 1998
EXPERIENCES
Stowers Institute for
Medical Research-March 2007-Present
Postdoctoral Fellow
International Conference
Cold Spring Harbor
Laboratory, Eukaryotic DNA replication-2001, 2003, 2005
Poster Presentation
PUBLICATIONS
1) Kim, J. H., Kim, H. D., Ryu, G. H., Kim, D. H., Hurwitz, J., Seo,
Y. S. (2006) Isolation of human Dna2 endonuclease and
characterization of its enzymatic properties.Nucleic
Acids Res., 34, 1854-1864.
2) Kim, J. H., Kang, Y. H., Kang, H. J.,
Kim, D. H., Ryu, G. H., Kang, M. J., Seo, Y. S. (2005) In vivo and in vitro studies of Mgs1
suggest a link between genome instability and Okazaki fragment processing.
Nucleic Acids Res., 33, 6137-6150.
3) Kim,
D.H., Lee, K. H., Kim, J. H., Ryu, G. H., Bae, S. H., Lee, B.
C., Moon, K. Y., Byun, S. M., Koo,
H. S., Seo, Y. S. (2005) Enzymatic properties of the Caenorhabditis elegans Dna2 endonuclease/helicase and a species-specific interaction
between RPA and Dna2. Nucleic Acids Res., 33, 1372-1383.
4) Ryu, G.H., Tanaka, H., Kim, D. H., Kim, J. H., Bae, S.H., Kwon, Y. N., Rhee, J. S., MacNeill, S. A., Seo, Y. S. (2004) Genetic and biochemical analyses of Pfh1
DNA helicase function in fission yeast. Nucleic Acids Res., 32, 4205-4216.
5) Kim, J. H., Kim, J., Kim, D. H., Ryu, G. H., Bae, S. H., Seo, Y. S. (2004) SCFhFBH1 can act as helicase
and E3 ubiquitin ligase. Nucleic Acids Res., 32, 2287-2297.
6) Bae, S. H., Kim, D. W., Kim, J., Kim, J. H., Kim, D. H., Kim, H. D., Kang, H. Y., Seo, Y. S. (2002) Coupling of DNA helicase and endonuclease activities of yeast Dna2 facilitates Okazaki
fragment processing. J. Biol. Chem., 277, 26632-26641.
7) Kim, J.,
Kim, J. H., Lee, S. H., Kim, D. H.,
Kang, H. Y., Bae, S. H., Pan, Z. Q., Seo, Y. S. (2002) The novel human DNA helicase hFBH1 is an
F-box protein. J. Biol. Chem., 277, 24530-24537.
8) Bae, S. H., Kim, J. A., Choi, E.,
Lee, K. H., Kang, H. Y., Kim, H. D., Kim,
J. H., Bae, K. H., Cho,
Y., Park, C., Seo, Y. S. (2001) Tripartite structure
of Saccharomyces cerevisiae Dna2 helicase/endonuclease.
Nucleic Acids Res., 29, 3069-3079.
9) Kim, J.,
Kim, D., Chung, J. (2000) Replication protein a 32 kDa
subunit (RPA p32) binds the SH2 domain of STAT3 and regulates its
transcriptional activity. Cell Biol Int., 24,
467-473.
10) Chung,
J., Park, E. S., Kim, D., Suh, J. M., Chung, H. K., Kim, J., Kim, H., Park, S. J., Kwon, O.
Y., Ro, H. K., Shong, M. (2000) Thyrotropin
modulates interferon-gamma-mediated intercellular adhesion molecule-1 gene
expression by inhibiting Janus kinase-1 and signal
transducer and activator of transcription-1 activation in thyroid cells. Endocrinology., 141, 2090-2097.
11) Koh, H., Jee, K., Lee, B., Kim, J., Kim, D., Yun,
Y. H., Kim, J. W., Choi, H. S., Chung, J. (1999)
Cloning and characterization of a nuclear S6 kinase, S6 kinase-related kinase
(SRK); a novel nuclear target of Akt. Oncogene.,
18, 5115-5119.