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Degrees

• 1995: B.S. in Biology, Union College, Schenectady, NY.
• 2002: Ph.D. in Biochemistry, Cellular and Molecular Biology, Johns Hopkins University School of Medicine, Baltimore, MD.

Awards

• 2003 Damon Runyon Cancer Research Foundation Post-doctoral Fellowship (2003-2005)
• 1995 Phi Beta Kappa
  

  Publications

• Oca de Montes R, Lee KK, Wilson KL. Binding Of Barrier-to-Autointegration Factor (BAF) To Histone H3 and Selected Linker Histones Including H1.1. Submitted to J. Biol. Chem.
  
• Lee, KK, Florens L, Swanson SK, Washburn MP, Workman JL.  The Deubiquitylation Activity of Ubp8 is dependent upon Sgf11 and its association with the SAGA Complex.  Mol Cell Biol. 2005 Feb;25(3):1173-82. 
  
• Lee KK, Prochasson P, Swanson SK, Florens L, Washburn M, Workman, JL. Proteomic Analysis of Chromatin Modifying Complexes in S. cerevisiae Identifies Novel Subunits. Accepted for publication in Biochem. Soc. Trans. 2004 Dec; 32 (Pt 6):899-903. 
• Lee KK, Wilson KL. All in the family: evidence for four new LEM-domain proteins Lem2 (NET-25), Lem3, Lem4 and Lem5 in the human genome. In: The Nuclear Envelope, Evans, D.E., Bryant, J.A., Hutchinson, C. (eds), Garland/Bios Scientific Publishers, Abingdon, pp 331-42.
  
• Fridkin A, Mills E, Margalit A, Neufeld E, Lee KK, Feinstein N, Cohen M, Wilson KL, Gruenbaum Y. Matefin, a Caenorhabditis elegans germ line-specific SUN-domain nuclear membrane protein, is essential for early embryonic and germ cell development. Proc Natl Acad Sci U S A. 2004 May 4;101(18):6987-92. Epub 2004 Apr 20.
  
• Mansharamani M, Graham DR, Monie D, Lee KK, Hildreth JE, Siliciano RF, Wilson KL. Barrier-to-autointegration factor BAF binds p55 Gag and matrix and is a host component of human immunodeficiency virus type 1 virions. J Virol. 2003 Dec;77(24):13084-92.
  
• Liu J, Lee KK, Segura-Totten M, Neufeld E, Wilson KL, Gruenbaum Y. MAN1 and emerin have overlapping function(s) essential for chromosome segregation and cell division in Caenorhabditis elegans. Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4598-603. Epub 2003 Apr 08.
• Holaska JM, Lee KK, Kowalski AK, Wilson KL. Transcriptional repressor germ cell-less (GCL) and barrier to autointegration factor (BAF) compete for binding to emerin in vitro. J Biol Chem. 2003 Feb 28;278(9):6969-75. Epub 2002 Dec 18.
• Mislow JM, Holaska JM, Kim MS, Lee KK, Segura-Totten M, Wilson KL, McNally EM. Nesprin-1alpha self-associates and binds directly to emerin and lamin A in vitro. FEBS Lett. 2002 Aug 14;525(1-3):135-40.
• Lee KK, Starr D, Cohen M, Liu J, Han M, Wilson KL, Gruenbaum Y. Lamin-dependent localization of UNC-84, a protein required for nuclear migration in Caenorhabditis elegans. Mol Biol Cell. 2002 Mar;13(3):892-901.
• Lee KK, Gruenbaum Y*, Liu J, Cohen M, Wilson KL. The expression, lamin-dependent localization and RNAi depletion phenotype for emerin in C. elegans. J Cell Sci. 2002 Mar 1;115(Pt 5):923-9. (* shared first authorship)
• Haraguchi T, Koujin T, Segura-Totten M, Lee KK, Matsuoka Y, Yoneda Y, Wilson KL, Hiraoka Y. BAF is required for emerin assembly into the reforming nuclear envelope. J Cell Sci. 2001 Dec;114(Pt 24):4575-85.
• Lee KK, Haraguchi T, Lee RS, Koujin T, Hiraoka Y, Wilson KL. Distinct functional domains in emerin bind lamin A and DNA-bridging protein BAF. J Cell Sci. 2001 Dec;114(Pt 24):4567-73.
• Shumaker DK, Lee KK, Tanhehco YC, Craigie R, Wilson KL. LAP2 binds to BAF.DNA complexes: requirement for the LEM domain and modulation by variable regions. EMBO J. 2001 Apr 2;20(7):1754-64. 
  
• Wilson KL, Zastrow MS, Lee KK. Lamins and disease: insights into nuclear infrastructure. Cell. 2001 Mar 9;104(5):647-50.
• Lee KK, Cohen M*, Wilson KL, Gruenbaum Y. Transcriptional repression, apoptosis, human disease and the functional evolution of the nuclear lamina. Trends Biochem Sci. 2001 Jan;26(1):41-7. (* shared first authorship)
• Lee KK, Gruenbaum Y, Spann P, Liu J, Wilson KL. C. elegans nuclear envelope proteins emerin, MAN1, lamin, and nucleoporins reveal unique timing of nuclear envelope breakdown during mitosis. Mol Biol Cell. 2000 Sep;11(9):3089-99.
• Desilva H, Lee K, Osley MA. Functional dissection of yeast Hir1p, a WD repeat-containing transcriptional corepressor. Genetics. 1998 Feb;148(2):657-67.
• Spector MS, Raff A, DeSilva H, Lee K, Osley MA. Hir1p and Hir2p function as transcriptional corepressors to regulate histone gene transcription in the Saccharomyces cerevisiae cell cycle. Mol Cell Biol. 1997 Feb;17(2):545-52.

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Email:kel@stowers-institute.org