Contact Information:

Education:

Institute of Molecular BioSciences, Massey University, New Zealand

Ph.D., Genetics 2005

B.Sc. Hons., Biochemistry, Physiological and molecular plant biology  2001

Publications:

1) Weake, V.M., and Workman, J.L. (2011). Histone Ubiquitination. In Regulation of Organelle and Cell Compartment Signaling, R.A. Bradshaw, and E.A. Dennis, eds. (Elsevier).

2) Schiemann, A.H., Li, F., Weake, V.M., Belikoff, E.J., Klemmer, K.C., Moore, S.A., and Scott, M.J. (2010). Sex-biased transcription enhancement by a 5' tethered Gal4-MOF histone acetyltransferase fusion protein in Drosophila. BMC molecular biology 11, 80.

3) Schiemann, A.H., Weake, V.M., Li, F., Laverty, C., Belikoff, E.J., and Scott, M.J. (2010). The importance of location and orientation of male specific lethal complex binding sites of differing affinities on reporter gene dosage compensation in Drosophila. Biochemical and Biophysical Research Communications 402, 699-704.

4) Weake, V.M., and Workman, J.L. (2010). Inducible gene expression: diverse regulatory mechanisms. Nature Reviews Genetics 11, 426-437.

5) Weake, V.M., Swanson, S.K., Mushegian, A., Florens, L., Washburn, M.P., Abmayr, S.M., and Workman, J.L. (2009). A novel histone fold domain-containing protein that replaces TAF6 in Drosophila SAGA is required for SAGA-dependent gene expression. Genes Dev 23, 2818-2823.

6) Weake, V.M., and Workman, J.L. (2009). Histone Ubiquitination. In Handbook of Cell Signaling, R.A. Bradshaw, and E.A. Dennis, eds. (Oxford:Academic Press), pp. 2449-2460.

7) Weake, V.M., and Workman, J.L. (2009). Hit and run: X marks the spot! Nature structural & molecular biology 16, 801-803.

8) Weake, V.M., and Workman, J.L. (2008). Clearing the way for unpaused polymerases. Cell 134, 16-18.

9) Weake, V.M., and Workman, J.L. (2008). Histone ubiquitination: triggering gene activity. Molecular cell 29, 653-663.

10) Weake, V.M., Lee, K.K., Guelman, S., Lin, C.H., Seidel, C., Abmayr, S.M., and Workman, J.L. (2008). SAGA-mediated H2B deubiquitination controls the development of neuronal connectivity in the Drosophila visual system. The EMBO journal 27, 394-405.

11) Weake, V.M., and Scott, M.J. (2007). The non-dosage compensated Lsp1alpha gene of Drosophila melanogaster escapes acetylation by MOF in larval fat body nuclei, but is flanked by two dosage compensated genes. BMC molecular biology 8, 35.

12) Guelman, S., Suganuma, T., Florens, L., Weake, V., Swanson, S.K., Washburn, M.P., Abmayr, S.M., and Workman, J.L. (2006). The essential gene wda encodes a WD40 repeat subunit of Drosophila SAGA required for histone H3 acetylation. Molecular and cellular biology 26, 7178-7189.

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